Mario Scarpa

I received my M.S. in Medical Biotechnology from the University of Naples Federico II, Italy and later I earned my international Ph.D. in Molecular Medicine and Pharmacology in the University of Ferrara, Italy. My PhD Project was based on my 3 years experience as Researcher-Visiting Scholar through the Molecular Virology, Immunology and Medical Genetics Department at the Ohio State University in Columbus (OH, USA). During this experience as a Researcher Visiting Scholar my research activity was focused on DDR pathways and on the plasticity of tumor cells to survive after radiotherapy and/or chemotherapy, both in vitro and in vivo. My project was based on the role of the Scorpin proteins as novel mediators of cellular DNA Damage response in lung cancer. These studies have led me to the analysis of the role and mechanisms of DNA Damage Response in cancer, focusing on their involvement in lung cancer development, progression and response to anti-neoplastic therapies. In 2016 I joined Dr. Maria R. Baer’s laboratory at University of Maryland Baltimore, Baltimore MD, USA. Here, my research program in the Department of Oncology of University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center was focused on signal transduction pathways in acute myeloid leukemia with Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) and preclinical development of novel therapeutic approaches to AML. In particular, it was focused on the regulated molecular mechanisms involved in AML following drug treatment. Now I am happy to enjoy in this team in Bern and ready for this new adventure to beat the cancer.